The PANSS is a 30-item clinical rating scale used to assess the severity of symptoms in individuals with schizophrenia¹

•What it measures: positive symptoms (7 items), negative symptoms (7 items), and general psychopathology symptoms (16 items)¹

•How it’s administered: a clinician interviews the patient and rates the severity of each symptom on a 7-point scale rated from 1 (absent) to 7 (extreme)¹

•Clinical use: primarily used to assess the severity of certain core symptoms of schizophrenia; also is commonly used to measure treatment effects and can aid in the management of schizophrenia²

•PANSS factors: factor analyses of the PANSS by Mohr and Marder have further refined symptom/item categorization into dimensions/factors of schizophrenia. Marder includes selected symptoms from both the negative and general psychopathology scales, while Mohr combines selected symptoms from the positive and general psychopathology scales^1,3,4

<sub>1. Kay SR, et al. Schizophr Bull. 1987;13(2):261-276. 2. Lehoux C, et al. Clin Schizophr Relat Psychoses. 2009;3(3):103-110. 3. Mohr PE, et al. Schizophr Res. 2004;71(1):83-95. 
4. Marder SR, et al. J Clin Psychiatry. 1997;58(12):538-546.</sub>